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Title : Another Reason Marijuana is Illegal: It Prevents The Spread of HIV
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Another Reason Marijuana is Illegal: It Prevents The Spread of HIV

The overwhelming evidence of the healing powers of marijuana and cannabinoids leave little doubt that the pharmaceutical industry is behind the laws of marijuana prohibition. The amount of research and validation of the truly remarkable nature of this herb is simply huge. According to new findings published in the journal PLoS ONE, researchers have now have now discovered that marijuana-like chemicals trigger receptors on human immune cells that can directly inhibit a type of HIV (HIV ) found in the final stage of AIDS.


The US Patent 6630507 was specifically initiated when researchers discovered that cannabinoids have specific antioxidant properties that It makes useful in the treatment and prophylaxis wide range of diseases associated oxidation, as ischemic diseases, age-related, inflammatory and autoimmune. Cannabinoids are found to have particular application as neuroprotective, for example to limit neurological damage following ischemic insults such as stroke and trauma, or in the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and HIV dementia .

The Netherlands became the first country to make cannabis available as a prescription drug in pharmacies to treat cancer, HIV and multiple sclerosis patients

Medical marijuana has been normally prescribed to treat pain, debilitating weight loss and appetite suppression in patients with advanced AIDS. However, Mount Sinai School of Medicine researchers have developed the first study to reveal how marijuana receptors found on immune cells - called cannabinoid receptors CB1 and CB2 -. You can influence the spread of the virus


Unfortunately, scientists will use the research on the effects of these receptors to develop new drugs in benefit of the pharmaceutical industry.

researcher and activist Jason marijuana Mihaldas says studies finally justify what the community in favor of marijuana has always know. "Decades of anecdotal and empirical evidence are now being validated by the scientific community, but it is unfortunate that they are using this research for their own selfish reasons - take marijuana from his medically effectively premium to one that will be medically ineffective with processing agents, altering what it was designed to do ... heal, "proclaimed Mihaldas.

"We knew that cannabinoid drugs like marijuana can have a therapeutic effect in AIDS patients, but do not understand how they influence the spread of the virus itself," said study author Cristina Costantino, PhD , postdoctoral fellow in the Department of Pharmacology and Therapeutics Systems at Mount Sinai School of Medicine. "We wanted to explore cannabinoid receptors as a target for pharmaceutical interventions that treat the symptoms of end stage AIDS and prevent progression of the disease without the undesirable side effects of medical marijuana."

non-psychoactive cannabinoids, as cannabidoil, are particularly advantageous for use because they avoid toxicity was found with psychoactive cannabinoids at high doses useful in the method of the present invention. CBD (cannabidiol), one of the main constituents of the cannabis plant has been medically proven to alleviate many diseases including inhibiting the growth of cancer cells. Recent studies have shown that is an atypical anti-psychotic effective in the treatment of schizophrenia. CBD also interferes with the amount of THC your brain processes, balancing the psychotropic effect of marijuana. That is precisely why the raw potency of cannabis is drawing attention.

HIV infects activated immune cells bearing the CD4 viral receptor, which makes these cells unable to fight infection. In order to spread, the virus requires that "resting" immune cells are activated. End-stage AIDS, HIV mutates so it can infect these resting cells, gaining entry into the cell by using a receptor called CXCR4 signaling. By treating the cells with a cannabinoid agonist that triggers CB2, Dr. Costantino and the Mount Sinai team found that CB2 blocked the signaling process, and suppressed infection in resting immune cells.

The Mount Sinai team infected the healthy immune cells with HIV, then he treated them with a chemical that triggers called CB2 agonist. They found that the drug reduces the infection of the remaining cells.

"Developing a drug that triggers only CB2 as is adjunctive treatment to standard antiviral medication may help alleviate the symptoms of the final stage AIDS and prevent the spread of the virus," said Dr. Costantino . Since HIV does not use CXCR4 to enhance immune cell infection in the early stages of infection, CB2 agonists appear to be an effective antiviral drug only in the late phase of the disease.

As a result of this discovery, the research team led by Benjamin Chen, MD, PhD, Assistant Professor of Infectious Diseases, and Lakshmi Devi, PhD, Professor of Pharmacology and Therapeutics Systems at Mount Sinai School of Medicine plans to develop a mouse model of the final phase of AIDS in order to test the effectiveness of a drug that activates CB2 in vivo.

Now that the scientific evidence was made public, a concerted effort must be made from all nations to eliminate marijuana prohibition laws. Ownership or possession of a plant should never be a crime and the origin and source of these laws are now coming to light.

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