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Title : The Data is Very Strong: Marijuana Plant Extract Stops Cancers From Spreading
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The Data is Very Strong: Marijuana Plant Extract Stops Cancers From Spreading

By Marco Torres

the data is very strong and there is no toxicity associated with a compound found in cannabis could halt the spread of many forms of aggressive cancer, scientists say.

The first study to show the antitumor properties of marijuana was presented at the American Association for Cancer Research meeting in Los Angeles in 2007, which shows that THC may activate biological pathways that stop division cell or block development of blood vessels feeding the tumors. Then became an object of research in synthetic THC for drugs like Erbitux from ImClone Systems Inc. and Vectibix from Amgen Inc ..

Now, researchers have found that the compound, called cannabidiol, had the ability "turn off" the gene responsible for metastasis in an aggressive form of breast cancer. Importantly, this substance does not produce the psychoactive properties of the cannabis plant.

The team at California Pacific Medical Center in San Francisco, first discovered five years ago their potential, after the cell proliferation of human breast cancer in the laboratory he stopped.

Last year published a study that found a similar effect in mice. Now they say they are on the verge of publishing new results of the study of animals that further extend these results.

non-psychoactive cannabinoids, as cannabidoil, are particularly advantageous for use because they avoid toxicity was found with psychoactive cannabinoids at high doses useful in the method of the present invention. CBD (cannabidiol), one of the main constituents of the cannabis plant has been medically proven to alleviate many diseases including inhibiting the growth of cancer cells. Recent studies have shown that is an atypical anti-psychotic effective in the treatment of schizophrenia. CBD also interferes with the amount of THC your brain processes, balancing the psychotropic effect of marijuana. That is precisely why the raw potency of cannabis is drawing attention.

Speaking to the San Francisco Chronicle, study co-leader Dr. Sean McAllister said: "preclinical trial data is very strong and no toxicity. there is really a lot or research to move forward with and to get people excited. "

While he, along with his colleague Dr. Pierre Desprez acknowledge that they are a little far from convert his find in a pill, which are already developing human test models. They hope to eventually test the drug in combination with current chemotherapies.
Professor Desprez had previously found that a protein called ID-1 seemed to play a role in causing breast cancer spreading. Meanwhile Dr. McAllister had discovered the cannabidiol had potential against cancer.


The pair came together to see if they could treat a particularly aggressive form of breast cancer called "triple negative". Thus, affecting 15 percent of patients, has three hormone receptors which target the most successful treatments. This cancer cells have high levels of ID-1.

When this cancer cells were exposed to cannabidiol were surprised to find that the cells not only stopped acting 'crazy', but also returned to a normal, healthy state.

They found that the compound had turned off the overexpression of ID-1, preventing their travel to distant tissues.

Other potentially treatable cancers are forms of leukemia, lung, ovary and brain cancers, also they have high levels of ID-1.

Dr. Desprez has a particular reason for wanting to create a treatment as soon as possible - her sister was recently diagnosed with aggressive breast cancer at the age of 41.

His condition is currently receptive to hormonal therapies but Professor Desprez fears that could happen again in a way that lacks hormone receptors.

He said, 'I want to be ready for that. There is a deadline. "

Cannabis is a class B drug that is illegal to have, give away or sell." If cannabis were discovered in an Amazon jungle today, people would be clambering to make greater use that could go the potential benefits of the plant, "said Donald L. Abrams, MD, Chief of Hematology and Oncology at San Francisco General hospital and professor of medicine at the University of California. Dr. Abrams is widely known for his research on applications medical cannabis. "Unfortunately, it brings a long and not so long history of being a persecuted plant," he added.

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