Researchers find way to use skin cells to kill cancer

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Title : Researchers find way to use skin cells to kill cancer
link : Researchers find way to use skin cells to kill cancer

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Researchers find way to use skin cells to kill cancer

id = " Only 30 percent of patients with glioblastoma, a form of brain cancer, survive past two years, because even if a surgeon removes the tumor, it is almost impossible to get invasive tendrils that spread in the brain and allow the tumor to regrow. Researchers at the University of North Carolina have pioneered a technique to turn skin cells into stem cells cancerosas- hunting in mice, they found and killed tumor cells remaining brain. The glioblastoma tumors are aggressive, fast-growing form astrocytes, cells that form the supportive tissue of the brain. Astrocytes reproduce quickly, and are compatible with a wide network of blood vessels, so the relatively rare cancer can be so difficult to treat according to the American Brain Tumor Association . "We wanted to find out if these neural stem cells induced in on cancer cells and whether they could be used to deliver a therapeutic agent," Dr. Shawn Hingtgen, assistant professor at the University of North Carolina, one press release . "This is the first time that direct reprogramming technology has been used to treat cancer." For the study, published in the journal Nature Communications , the researchers reprogrammed skin cells called fibroblasts to become neural stem cells to produce a protein to destroy tumors. The cells in the skin to produce collagen and connective tissue, hunt and kill cancer cells. The cells are inserted into mice and kept in place using a physical matrix in order to keep them there long enough to look for cancer cells in the area time. Depending on the type and the specific location of the tumor, the researchers report that increased the survival of mice by 160-220 percent. Future research will focus on the use of human stem cells and test more effective anti-cancer drugs that can be combined with neural stem cells reprogrammed
Source :. http: //www.upi.com/


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