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Title : Did Angelina Jolie Make A Mistake By Acting On The 'Breast Cancer Gene' Theory?
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Did Angelina Jolie Make A Mistake By Acting On The 'Breast Cancer Gene' Theory?

By: Sayer Ji

The "prophylactic" removal of the breasts of women because of the condition of BRCA1 / BRCA2 has become a popular worrying trend, and each time held in the mainstream media and medical facilities as a reasonable option. But the scientific evidence itself refute this approach?

The recent announcement of Angelina Jolie in a New York Times opinion he had a "preventive" double mastectomy, because of its BRCA1 / BRCA2 State has worrying implications, some of which we covered late last year regarding Allyn Rose, 24 contestant old miss America, who announced that he would be subjected to a double mastectomy to "prevent" breast cancer .

beyond the fact that as high profile celebrities for their decisions affect millions perception of women in the process, are likely to be more acceptance of the concept, its decisions also reflect profound misconceptions about the risk of disease genes mediated deeply embedded in the popular consciousness, which is prevalent medical opinion is almost immune.

first, there is a common misconception about the role that genes called susceptibility to breast cancer, BRCA1 and BRCA2, playing in the risk of breast cancer disease and prognosis. BRCA mutations vary widely by ethnicity and are very rare in the general population, so as NBCNews.com recently reported "The Working Group Preventive Services of the United States recommends that only women with a strong family history, which even think getting a BRCA gene test is only 2 percent of American women ". But even in those in which a BRCA mutation, the genes themselves, not only make the disease is identified.

Despite the negative common place of the "evidence-based medicine" to recognize actual evidence genetics, we moved into an era post -genómica more than a decade after the completion of the first draft of the entire human genome in 2000. at that time, the central dogma of molecular biology - our DNA that controls the expression of proteins, and therefore the disease risk - was disproved. not even enough to account for the 100,000 proteins in the human body

As a result, we now have to accept that factors outside the control of gene known - our genome containing about 20,000 genetic instructions found as epigenetic factors, and largely determined by a combination of nutrition, psycho-spiritual states that feed back into our physiology, factors of lifestyle and environmental exposures, are as high as 95% of what determines the risk of disease. In fact, even the psychological trauma associated with a cancer diagnosis can lead malignant tumor through multidrug resistance adrenaline mediated drug [ i ] and according to a study by the recent NEJM, lead to a 26 times higher risk of heart-related within seven days after diagnosis deaths. [ II ]

Given this fact, the decision Jolie to have a bilateral mastectomy in order to remove from your body the breast tissue containing the BRCA1 / BRCA2 genes are known interfere with the repair of DNA damage induced by radiation, rather than focusing on reducing or eliminating all future exposure to radiation of their breasts, or incorporating hundreds of nutritional components experimentally confirmed to protect against radiation and genotoxic lesions associated with breast, reflects a faith coated iron in the inevitability of cancer genes driven vis-à-vis a fundamentally impotent issue facing confidence in the body's ability to prevent and cure all diseases, assuming you have the right conditions.

Another common misconception is that you either have or do not have the "Braca gene" as if they were monolithic entities, evaluated with the certainty of white and black a pregnancy test. It's a little known fact that thousands of "mutations" in the BRCA1 and BRCA2 genes have already been identified and characterized at the molecular level, adding much more complexity to the picture that the current level of medical knowledge can claim become convincing statistical risk calculations and viable treatment recommendations.

These mutations are technically known as polymorphisms of genes present variations of a gene naturally occurring in more than 1% of the population. come as a surprise to many to know that some of these so called "mutations" actually reduce the risk of breast cancer. variation BRCA1 K1 183R is inversely related to cancer risk, leading the authors of an opinion on the subject entitled "The case against BRCA1 and 2 testing," to conclude: "It appears that some polymorphisms may actually have a protective effect. " [ iii ] on the other hand, there is research that shows that BRCA2 mutation carriers and noncarriers have specific similar breast-specific mortality from breast cancer, cancer rates [ iv ] and that although BRCA positive patients have more frequently negative prognostic factors, prognosis seems to be equal or better than in patients with normal, also known as wild-type BRCA. [ v ]

Another blind spot on in making the decision Jolie is that approximately 70,000 breast cancers (31% of annual diagnoses of breast cancers) are misdiagnosed by the great breast 'consciousness' and the complex treatment cancer each year. [ vi ] These are not only the so-called "stage zero" breast cancers, such as Ductal carcinoma in situ (DCIS), which certainly should be reclassified as normal variations noncancerous morphology breast, but 50% are known as the early stages of invasive breast cancers "["estudiovistaNEJM[analysis video here ].

how many of these women who have been diagnosed with mammography detected breast cancer and then a follow-up BRCA believed that the gene must have therefore "caused" the "cancer"? The popularization of this crude way of understanding natural variations, sometimes self-limiting in morphology breast as cases of "breast cancer" is itself a malignant tumor that must be prevented and treated with healthy doses of the same " evidence "that the so-called '' medical system based on the evidence says have as a differentiating factor from other, older, plant and medical traditions based on nutrition.

last November, an article published in NEJM found that 1.3 million women in the United States is over-diagnosed and overtreating for so-called "breast cancer" in the last 30 years. These abnormal results were detected by screening breast never have progressed to cause damage in women who were diagnosed. These women, while essentially iatrogenic medicine victims are given standard treatment options, including mastectomy, lumpectomy, radiation, chemotherapy, were considered statistically as "survivors" whose lives were saved by the medical establishment, and these cases further inflated statistics to make the impression that interventions conventional treatment are much more effective than they actually are.

Given these facts, the decision Jolie hides a dark her side, like other millions of American women, they are fully aware of. For example, look at the rise of social response Myriad Genetics, holders of the patent human genes BRCA1 / BRCA2, shortly after the announcement of Jolie in this article Yahoo Finance published today: Myriad Genetics shares rise after Angelina Jolie mastectomy .

the company based in Utah, contrary to popular opinion, owns patents on the BRCA genes (men who have too). And not only that, as a recent article board explains:

[Myriad Genetics] claims to own the rights of any proof of the presence of two critical genes associated with breast cancer , and it has been applied mercilessly that right, but his proof is lower than that Yale University was willing to provide a much lower cost. The consequences have been tragic: thorough test, affordable identifying high-risk patients saves lives. Blocking these tests takes lives. Myriad is a true example of an American society for the benefit outweighs all other values, including the value of human life.

Given the fact that powerful companies, profit stand to reap deep financial benefit from the spread of a theory of simplified driven gene susceptibility to breast cancer, caution must be exercised in the jump in the media and medical car by displaying increasingly popular decision Jolie uncritically. Note also that women who undergo these mastectomies often opt for breast implants which in turn have been linked to cancer, as we discussed in our article last year "implemented: Myth implant free breast cancer, " and only were recently linked with cancer more aggressive breast and lower survival rates of breast cancer.

what we want it is true when it comes to understanding the risk of breast cancer, natural history, and what preventive and therapeutic measures should be used to reduce its progression and the associated suffering. Unfortunately, however, the industry influence breast cancer extends from academia to government, from cubes of KFC fried chicken with guns shaped pink ribbon Smith & Wesson brand. The more important to read between the lines, and remember that we alone are responsible for the education of ourselves, so that a truly informed decision possible.

Please use our guide health Cancer breast for direct access to the peer-reviewed and published in interventions natural and comprehensive maternal health research: health Guide: breast Cancer

Resources
[i] GreenMedinfo .com stress hormones found to cause cancer resistant to treatment
[ii] GreenMedInfo.com Research: some diagnoses can kill you faster than cancer
[iii] Cheryl Lin, Tina Sasaki, Aaron Strumwasser, Alden Harken. The case against BRCA 1 and 2 tests. Surgery. 2011 Jun; 149 (6): 731-4. PMID: 21621683
[iv] Mario Budroni, Rosaria Cesaraccio, Vincenzo Coviello, Ornelia Sechi, Daniela Pirino, Antonio Cossu, Francesco Tanda, Marina Pisano, Palomba Grazia, Giuseppe Palmieri. Role of BRCA2 mutation status in overall survival in patients with breast cancer Sardinia. BMC Cancer. 2009; 9: 62. Epub 2009 February 20. PMID: 19232099
[v] Andrea Veronesi, Giacomi Clelia, Maria D Magri, Davide Lombardi Martina Zanetti, Cristina Scuderi, Riccardo Dolcetti, Alessandra Viel, Diana Crivellari, Ettore Bidoli, Mauro Boiocchi. familial breast cancer: characteristics and evolution of BRCA 1-2 positive and negative cases . BMC Cancer. 2005; 5: 70. Epub July 2005. 4. PMID: 15996267
[vi] New England Journal of Medicine Effect of three decades of mammographic screening on Breast-Cancer Incidence
Source: greenmedinfo

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