Human Trials For A Vaccine That Destroys Cancerous Tumors Just Began

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Title : Human Trials For A Vaccine That Destroys Cancerous Tumors Just Began
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Human Trials For A Vaccine That Destroys Cancerous Tumors Just Began

id = " A newly developed vaccine that researchers hope will prove effective in destroying tumors cases where other treatments have failed currently being tested in clinical trials in the UK the first two participants have already been injected with the drug at Guy's Hospital in London, and a total of about expected that 30 patients to participate in the study over the next two years. Similar to how vaccines protect us from certain infections manner, treatment tries to recruit body's immune system itself to attack and destroy entities specific - in this case the cancer cells. Typically, the various components of the immune system - including White blood cells and T cells - protect against cancer to kill tumor cells, but some tumors are capable of evade these natural defenses. When this occurs and cancer develops at an advanced stage, the immune system is often suppressed . It is believed that many factors to be responsible for this effect, from the ability of tumor cells to damage the immune cells, a decrease in white blood cells when the cancer spreads to the bone marrow. Vaccines usually work by injecting a patient with small amounts of antigens , substances that are capable of eliciting an immune response, which stimulate the body to produce antibodies that they specialize in labeling and the destruction of that particular entity. The ability to generate such antibodies is maintained for a period of time, meaning that the immune system can then defend against future cases of the same disease. Accordingly, the new vaccine is being tested consists of small fragments of an enzyme found in cancer cells. Called human telomerase reverse transcriptase (hTERT), that regulates the length of the protective caps called telomeres of chromosomes, which allows cells to divide continually. Scientists are hopeful that this will stimulate the patient's immune system to produce antibodies that can target this enzyme, which facilitates the destruction of cancer cells. To give the process a good start, the vaccine is combined with low doses of chemotherapy in order to kill some of the tumor cells and the immune system desinhibir. The researchers behind the trial believe the vaccine could be effective for all types of solid tumors, and are testing safety and efficacy in patients whose cancer has been diagnosed as terminal. Among them is 35-year-old Kelly Potter, who was diagnosed with advanced cervical cancer last summer, but says that participation in the study has "changed [her] life for the better," adding "it is fantastic to be part of something that could be innovative."

Source "http://www.iflscience.com/


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