Title : Yummy! Your Liver May Be 'Eating' Your Brain
link : Yummy! Your Liver May Be 'Eating' Your Brain
Yummy! Your Liver May Be 'Eating' Your Brain
body fat Too the liver uses a lot of PPAR to metabolize fat, a protein that also used to regulate brain memory.
Your liver could be "eat" the brain , new research suggests.
People with extra abdominal fat are three times more likely than thin people to develop memory loss and dementia later in life, and now scientists say they can know why .
seems that the liver and hippocampus (memory center in the brain), share a desire for a certain protein called PPAR. The liver uses for PPAR burn belly fat ; PPARalpha the hippocampus used to process memory.
In people with a lot of belly fat, the liver has to work overtime to metabolize fat, and uses all the PPAR - first ozone local stores and then attack the rest of the body, including the brain, according to the new study.
The process starves essentially the hippocampus of PPAR, hampering memory and learning, Medical Center researchers at Rush University in Chicago, wrote in the study, published in the current issue Cell journal reports.
Other press reports are not correct in pointing out that the researchers established that obese individuals were 3.6 times more likely than thin people develop dementia. That finding goes back to a 2008 study by researchers at the Kaiser Permanente Division of Research in Oakland, California.
In another study, described in a 2010 article in the journal Annals of Neurology, researchers from the School of Medicine at Boston University found that the greater the amount of belly fat, the greater the brain shrinkage in old age .
The surprising discovery in the new study is that the hippocampus uses PPAR to process memory and learning, and this is a possible reason for the connection between belly fat and dementia and / or loss memory.
Researchers at Rush University, led by professor of neurosciences Kalipada Pahan, raised mice that were deficient in PPAR. Some mice had normally PPARalpha in the liver, but impoverished PPARalpha in the brain, and had poor memory and learning ability. PPARalpha other had normal brain but not liver, and showed normal memory, as expected.
When the researchers injected PPAR in the hippocampus of mice deficient in PPAR, learning and memory improved, Pahan said.
"Further research should be conducted to see how we could potentially keep in regular PPAR [human] brain in order to be resistant to loss of memory," Pahan LiveScience.
therefore PPAR provides a new avenue to explore for a treatment or cure for Alzheimer's disease , dementia and problems related to memory and cognition loss, Pahan said.
Losing your belly fat will not hurt, either.
By Christopher Wanjek
SOURCE
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