Title : THE WORLD MOST POPULAR HERBS – SLIPPERY ELM (ULMUS RUBRA) HEALTH BENEFITS AND SIDE EFFECTS
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THE WORLD MOST POPULAR HERBS – SLIPPERY ELM (ULMUS RUBRA) HEALTH BENEFITS AND SIDE EFFECTS
Slippery elm is a genus Ulmus, belonging to the Ulmaceae, native to eastern North America family. The herb has been used in traditional medicine to treat wounds, boils, ulcers, burns, skin inflammation, relieve cough, sore throat, diarrhea, stomach problems, etc. health benefits
1. Antioxidants and anti-cancer effectsIn determining the antioxidants against cancer and the effects of Essiac tea prepared from a mixture of four herbs Arctium lappa, Rumex acetosella, Ulmus rubra and Rheum officinale
found that Essiac inhibits lipid peroxidation by hydroxyl radicals induced by up to 50% at the concentration of 50% tea preparation. These data indicate that Essiac tea has potent antioxidant activity and DNA-protecting properties that are common to natural anti-cancer agents. This study may help explain the mechanisms underlying the reported anti-cancer effects of Essiac, according to "Essiac tea: scavenging reactive oxygen species and the effects on DNA damage" Leonard SS, Keil D, Mehlman T suitable S, Shi X, Harris GK.
2. Breast cancer
In the investigation of the effect of Essiac and Flor-Essence (Resperin Canada Limited, Waterloo, Ontario, Canada), a mixture of at least four herbs (burdock root [Arctium lappa], Indian rhubarb [Rheum palmatum], sorrel [Rumex acetosella], and the inner bark of elm [Ulmus fulva or U. rubra]) agnaist breast cancer found that Flor-Essence and herbal tonics essiac 1%, 2%, 4% and 8% stimulate cell proliferation relative to untreated controls in both estrogen receptor-positive (MCF 7 and T47D) and negative estrogen receptor (MDA-MB-231 and MDA-MB-436) cell lines. Exposure to tonics also produced a dose dependent increase in luciferase activity in ER dependent MCF-7 cells. 10 (-7) M concentration of ICI 182,780 inhibits the induction of luciferase activity dependent ER by Flor-Essence and Essiac, but did not affect cell proliferation, according to "Essiac and Flor-Essence herbal tonics stimulate growth in vitro human cells of breast cancer "by Kulp KS, Montgomery JL, Nelson DO cutter B, ER Latham, Shattuck DL, DM Klotz, LM Bennett.
3. Inflammatory bowel disease
In the investigation of medicinal plants used by patients for the treatment of inflammatory bowel disease includes elm, fenugreek, devil's claw, he found that the six herbal remedies have antioxidant effects. Fenugreek is not a superoxide scavenger, while the Mexican yam not inhibit radical generation by inflamed biopsies. slippery elm, fenugreek, devil's claw, tormentil and Tong Wei Ning deserve a formal evaluation of new therapies in inflammatory bowel disease, according to "antioxidant effects of therapies herbal used by patients with inflammatory bowel disease: study in vitro "Langmead L, Dawson C, C Hawkins, Banna N, S Loo, Rampton DS.
4. inflammatory conditions
The evaluation protocols fo hybrid combine, two, or three drugs with several nutritional therapies or immune-based, indicated that the objective is to obtain the benefits of protease inhibitors and viral resistance without side effects including problems with fat metabolism and cholesterol levels. natural treatments for inflammatory diseases are also described. Options include licorice root, ginger root, and elm, accoridng to "hybrid protocols, and natural treatments for inflammatory diseases"
5. prostate cancer
in determining Essiac is a complementary and popular alternative (CAM) which is used by many cancer patients in North America, reported that low doses of Essiac, the increased proliferation of these T cells was demonstrated, but at higher doses was Essiac inhibitor T cell proliferation Essiac the same doses which stimulated spleen cells were inhibitors LNCaP cell proliferation and concluded from Essiac preparations that may be able to inhibit tumor growth while enhancing the immune response to antigenic stimulation cells. This can be especially valuable in immune-suppressed individuals.according to "Inhibition of cell proliferation by Essiac prostate cancer" by Ottenweller J, K Putt, Blumenthal EJ, Dhawale S, SW Dhawale.
6. disease prevention
The evaluation of the activity of antioxidant Essiac , fibrinolytic, anti-microbial, anti-inflammatory, immune modulation, the specific cytotoxicity of the cell, and the impact on cytochrome P450 enzyme pathways (CYP450). Essiac found that exhibited significant antioxidant activity in the ABTS assay. A 20-fold dilution Essiac also exhibited significant immunomodulatory effects, specifically through the stimulation of granulocyte phagocytosis, increasing activation of CD8 + cells, and inhibition of inflammatory pathways moderately. Essiac exhibited significant specific cytotoxicity toward cells epithelial ovarian carcinoma (A2780) cell. Importantly, a dilution of 20 times Essiac showed significant inhibition of CYP450 enzymes several, especially CYP1A2 (37%) and CYP2C19 (24%). Essiac demonstrated dependent inhibition dose clot fibrinolysis., According to "in vitro of compound analysis herbal essiac" bySeely D, Kennedy DA, Myers SP, Cheras PA, Lin D, Li R, Cattleya T, Brent PA, Mills E, Leonard BJ.
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