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Title : Common Painkillers Found to cause Increased Long Term Pain
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Common Painkillers Found to cause Increased Long Term Pain

There is mounting evidence that the opioid analgesics such as morphine and oxycodone may in some cases actually make the pain worse over time. This is partly because it is used more than one opioid analgesic, the higher the dose required to have the same effect in the future.

However, the new findings show that analgesic use over time also makes the body more sensitive to pain sensations -. Which in turn feeds the need for even higher doses

This insidious effect, called hyperalgesia, renderings pain medication less and less effective for the relief of chronic pain. Because of this, people come to increasing amounts of these drugs, increasing their risk of side effects and dependence.

Analgesics have a long list of negative side effects

A recent study using rats examined the interaction between nerve injury and opiates, and the results were alarming. Apparently opioid analgesics trigger a chain reaction of signals related to immunity within the spinal cord. These signals actually amplify the pain rather than dulling it. The effect continued even after the drug left bodies of the subjects, the researchers found.

Many of the side effects of analgesics are well known. In addition to physical dependence and addiction, can cause constipation, nausea, vomiting, dizziness and breathing problems. Other side effects of analgesics may include hyperalgesia, delayed gastric emptying, hormonal dysfunction, immune dysfunction, myoclonus and muscle stiffness.

However, the most dangerous effect potential of opioid analgesics is the overdose and death. Overdose deaths from prescription painkillers have quadrupled in the last two decades as the rate of prescription of these drugs has increased.

opioid analgesics cause increased sensitivity to pain

hyperalgesia is clearly part of this equation, because it forces people to take more and more of a drug to feel the same level of relief. In addition to slow breathing to dangerous levels, high doses of these drugs seem to alter the human nervous system in a way that amplifies pain signals. The person then craves most analgesics, even after the original injury or medical problem resolved .

These results were supported by the rat study and further justified by the fact that many people taking opioid medications - before surgery. - More pain long they feel after the procedure

seems that injuries and opioid analgesics affect the cells of the spinal cord called microglia, which are security guards nervous system signs of infection are . Release molecules that activate neurons in the spinal cord that create pain signals in the brain signaling. Opioids make these much more sensitive to be activated microglia. While this may not be the only process that contributes to increased sensitivity to pain appears to be an important factor.

Find safer alternatives to opioids

The list of dangerous side effects of opioid analgesics is formidable, so the need to find safe alternatives to an urgent matter. Some of the best natural remedies for pain include :. vitamin C holistic treatments like acupuncture, acupressure, reflexology and massage , willow bark, turmeric, cloves and

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