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Title : Neem extract shows promise in pancreatic cancer treatment
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Neem extract shows promise in pancreatic cancer treatment

New York: A natural extract derived from Neem tree could potentially be used to treat cancer of the highly lethal pancreatic, according to a team of researchers, including scientists of Indian origin . the results revealed that nimbolide, an isolated active molecule Neem tree (Azadirachta indica), can stop the growth and spread of pancreatic cancer without harming normal, healthy cells. "The nimbolide promise has proved is amazing, and the specificity of treatment to cancer cells more than normal cells is very intriguing," said Rajkumar Lakshmanaswamy, associate professor at Texas Tech University Health Sciences Center El Paso in the US .. pancreatic cancer has the highest mortality rate of all cancers with 94 percent of patients die within five years of diagnosis. The cancer grows rapidly and currently there are no effective treatments available. The study, Lakshmanaswamy and colleagues observed that nimbolide was able to reduce the capacity of migration and invasion of cells of pancreatic cancer by 70 percent - meaning that cancer cells become aggressive and spread. And that is promising, the researchers said. In humans, this migration and invasion - or metastasis -. Of pancreatic cancer to other parts of the body is the main cause of mortality treatments Nimbolide also induced cell death cancer, causing the size and number of colonies of cells of pancreatic cancer dropwise to 80 percent. "Nimbolide seems to attack pancreatic cancer from all angles," Lakshmanaswamy said. What is more, the compound Neem not damage healthy cells, both in vitro and in vivo studies. "Many people in India actually eat neem and has no harmful side effects, suggesting that the use of nimbolide of pancreatic cancer will not cause adverse effects, such as chemotherapy and radiation usually do" , lead author of the study Ramadevi Subramani, a postdoctoral researcher at Texas Tech University Health Sciences Center, said. The findings appeared in the scientific journal reports. While the results are promising, Lakshmanaswamy said there is still a long way to go before nimbolide can be used to treat pancreatic cancer in humans. The researchers said they plan to further investigate the mechanisms behind cancer plant extract.

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