Title : Gene Therapy To Restore Health
link : Gene Therapy To Restore Health
Gene Therapy To Restore Health
Now there are several methods of gene therapy to restore the health of the most sophisticated practices such as gene therapy, this method intends to transfer genetic material with the aim of preventing or curing diseases. In many cases, a genetic disease where the gene is damaged or not this method involves the transfer of functional version of the gene body disease, in order to correct defects. It is a very simple idea, but as we shall see its practical realization has several problems that must be faced.
is done first gene isolation. are part of the DNA genes containing the information needed to synthesize proteins. It aims to transfer the gene transfer is a particular section of DNA. Genetic diseases are caused by different genetic changes. The first action in this method is to identify the genes responsible for this disease. with molecular biology techniques, you can buy a piece of DNA containing the genes. This step is called isolation or cloning of genes. interference when gene therapy. with advances in molecular biology first step is relatively simple. When the isolation of many genes that cause genetic diseases, can be found each week. This situation shows what the purpose of gene transfer. action in vivo methods involves the transfer of DNA in tissues or cells of the patient.
ex vivo procedure, DNA is first transferred to the isolated cells previously cultured in the laboratory. therefore modified network and isolated cells can be introduced into the patient. Then this method is indirect and longer, but offers the advantage of better transfer efficiency and the ability to select and expand the modified cells before reintroducing do.
When the transfer of DNA in vivo has the same target genes transferred into the cell, the gene must produce large quantities of protein to correct a genetic defect that occurs . when injecting DNA into cells or tissue being treated. Because these systems are very inefficient when DNA has almost no effect on the cells. This step requires an injection of individual cells or patient cells.
Even all techniques for transferring genetic material involves the use of vectors to carry the DNA into the host cell. methods of gene therapy to help restore the health of many people.
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