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Title : Smart Insulin Patch Controls Blood Sugar Levels For 10 Hours
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Smart Insulin Patch Controls Blood Sugar Levels For 10 Hours

id = " People suffering from diabetes must constantly monitor their sugar intake and the regularly inject insulin to regulate sugar levels in the blood. The injections are often painful and imprecise, but promises a new method to change that. A team of researchers from North Carolina has created a patch smart insulin. A similar proof of concept was introduced last year, showing that it was able to maintain levels of blood sugar under control in mice with type-1 diabetes. The latest prototype demonstrates that the technology can respond quickly to the clouds sugar levels in the blood and lowering them significantly for up to 10 hours in diabetic mice. The new smart patch insulin, presented in advance materials, is a square with small needles polymeric coating. Living hosts biopolymer beta cells, which are responsible for insulin production. These cells do not function properly in people suffering from diabetes. Attempts to transplant beta cells have occurred since the 1970s, and the first successful transplant only happened in 1990. Unfortunately, the rejection rate of this type of intervention is quite high. "In this study a possible solution to the hard problem of rejection, which has long plagued studies on transplantation of pancreatic diabetes cells is provided," said lead author Zhen Gu, assistant professor in the whole department of UNC / NC state of biomedical engineering, said in the statement. "In addition to demonstrating that we can build a bridge between physiological signals in the body and these therapeutic cells outside the body to maintain glucose levels under control." The capsule of beta cells is not the only novelty in the new smart patch. The needles are covered with three chemicals that act as amplifiers "glucose signal". This trick ensures that beta cells know when the level of blood sugar is increasing so they can start producing insulin. smart insulin patch is promising, but will have to go through more changes, preclinical testing and human trials finally. However, the technology could have an impact on 387 million people worldwide suffering from diabetes. "Managing diabetes is difficult for patients because they have to think about it 24 hours a day, seven days a week, for the rest of their lives," he said co-author John Buse said, MD, Ph.D., professor of medicine at the UNC School of Medicine and director of the Diabetes Care Center UNC and NC translational and clinical Science Institute. "These approaches are very smart insulin interesting because they hold the promise of giving patients a rest period with respect to self-care of diabetes. It would not be a cure, but they desperately need a vacation."
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