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Title : Drinking Patterns Linked to Liver Cirrhosis
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Drinking Patterns Linked to Liver Cirrhosis

Drinking every day significantly increases the risk of liver cirrhosis, according to a new study. While it is generally believed that cirrhosis is a function of the volume of alcohol consumed, it reveals a new extensive research evidence that consumption patterns can also significantly increase the risk of cirrhosis.

"For the first time, our study points to a difference in risk between daily drinking and eating five or six days a week in the male population in general, since previous studies were conducted in the misuse of alcohol and patients referred for liver disease and drink every day compared to 'pattern of binge eating "or" drinking episodes, "" lead researcher Gro Askgaard, MD, Department of Hepatology, hospital University of Copenhagen, Rigshospitalet, and the National Institute of Public Health at the University of Southern Denmark, Copenhagen, Denmark, said in a news release. "Since the details of alcohol-induced liver injury are unknown, we can only speculate the reason may be that daily alcohol exposure worsens liver damage or inhibits liver regeneration. "

the latest study included data from 55.917 people between the ages of 50 and 64. the researchers found that 257 85 men and women develop alcoholic cirrhosis, which is equivalent to an incidence rate of 66 in men and 19 in women per 100,000 people.

The results of the study revealed that daily consumption significantly increases the risk of alcoholic cirrhosis in men. The researchers also found that recent alcohol was a stronger predictor of alcoholic cirrhosis alcohol for life.


"Previous studies regarding alcohol consumption and the risk of life to opposite conclusions cirrhosis reached alcoholic, for example, if a high prior level of the amount of alcohol predicted future risk, even after cutting, "he added Askgaard. "From a clinical standpoint, this is relevant to implement the evidence-based advice, and from a public health perspective, you can target health interventions for the general population."

"This is a timely contribution on one of the most important, if not the most important risk factor for liver cirrhosis worldwide risk because our general knowledge about patterns of consumption and cirrhosis liver is scarce and partly contradictory, "concludes the expert said Jürgen Rehm, Ph.D. , Director of the Department of Social and Epidemiological Research Centre for Addiction and Mental Health, Toronto, according to the press release. "The work of Askgaard and his colleagues not only increases our knowledge, but also raises questions for future research. The issue of patterns of excessive alcohol consumption and mortality is far from being solved, and there may be genetic differences and other covariates yet undiscovered, which play a role and could explain the different empirical results. "

the results are published in the journal of Hepatology.

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