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Experts fear diseases 'impossible to treat'

alarming increase of bacteria resistant to antibiotics government report is
Britain faces a "massive" increase in poisoning resistant to antibiotics caused by E. coli bacteria blood. - bring the spectrum of diseases that are impossible to treat
experts say that the growth of antibiotic resistance now masquerading as a major threat to global health as the emergence of new diseases such as AIDS and pandemic influenza.
professor Peter Hawkey, a clinical microbiologist and president of the working group resistance antibiotics government, said antibiotic resistance had become the equivalent of medicine of climate change.
the "slow but insidious growth" of resistant organisms threatened to turn common infections in incurable diseases, he said. Already, an estimated 25,000 people die each year in the European Union against resistant bacterial infections to antibiotics.

"It's a problem all over the world - there are no limits," he said. "We have very good policies on the use of antibiotics in humans and animals in the UK. But we are not alone. We have to think globally." Between 2005 and 2009 the incidence of bacteremia "" E. coli [the presence of bacteria in the blood] increased by 30 percent, from 18,000 to more than 25,000 cases. Those who are resistant to antibiotics have increased from 1 percent in early century to 10 percent.
"Only one in 20 of infections with [resistant] E. coli is a bacteremia, so the above data are just the tip of the iceberg of people infected "says a report by the group of professor Hawkey, commissioned by the Department of Health and Affairs Department for Environment, Food and rural Affairs.
Dame Sally Davies, medical director the Government has committed £ 500,000 to fund research into the threat. Pharmaceutical companies have lost interest in the development of new antibiotics, as it is increasingly difficult to find new agents and is not commercially viable - taking antibiotics for a few days, compared to, for example, a heart medicine that can be taken for life.
"there are only so many antibiotics available and we lose becomes more and more difficult to replace," said Professor Hawkey.

The rapid increase in blood poisoning E. coli are believed to be related to the aging population. E. coli is a common cause of urinary tract infections, but can also cause wound infections after surgery or injury. These are considered minor conditions, but if they became untreatable they would be life threatening.
E. coli infections represent a much larger than MRSA problem because the bacteria is more common . Only one in 10 people are carriers of MRSA, E. coli but is present throughout the world. "Those who are sick [with E.coli] are rare - but because it is so common that it is a big problem," said Professor Hawkey
The use of standard antibiotic regimens, there is a one. in 10 chance that the treatment of an infection of E. coli fail because the fault is resistant. But as the number of resistant infections increase, there will be increasing pressure to use more powerful antibiotics called carbapenems, which are the last line available. And the resistance is already emerging. "In the last two or three years we have seen [organisms] develop which destroy carbapenems. That's a big concern," said Professor Hawkey. The warnings follow increasing reports in Europe of patients with infections that are almost impossible to treat. In November, the European Centre for Disease Control and Prevention (ECDC) to 50 percent of cases of blood poisoning bacteria K. pneumoniae with a common cause of urinary and respiratory infections are resistant to carbapenems in some countries.
across Europe, the percentage of K. pneumoniae resistant to carbapenem has doubled from 7 percent to 15 percent, the ECDC said. Marc Sprenger, director, said: "The situation is critical We must declare war against these bacteria."
Meanwhile, the Agency for Health Protection UK warned doctors in October. to abandon a drug usually used to treat a disease common sexually transmitted, because it was no longer effective. The agency said that gonorrhea - which caused 17,000 infections in 2009 - should be treated with two drugs instead of one
Explanation: how insects adapt to beat antibiotics [
insects are like all other forms of life have to adapt to survive. Unlike humans, however, for which the evolution of thousands of years is measured, reproduction is so rapid among bacteria that can change in months or years.
With the introduction of a new antibiotic, natural selection is going to work. Most bacteria are killed by the new drug, but the natural variation that occurs in any species means a few examples may, by chance, have some quirk in their genetic structure that allows them to survive.
These bacteria are then selected out by the antibiotic, which kills the rest. Mutant bacteria grow in number until they become the dominant species Source:. The Independent

"Experts fear diseases 'impossible to treat'", article source: riseearth.com

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